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Ubiquitin-like protein FAT10 promotes renal fibrosis by stabilizing USP7 to prolong CHK1-mediated G2/M arrest in renal tubular epithelial cells

Renal fibrosis is the pathological hallmark of chronic kidney disease that is influenced by numerous factors. Arrest of renal tubular epithelial cells (RTECs) in G2/M phase is closely correlated with the progression of renal fibrosis; however, the mechanisms mediating these responses remain poorly d...

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Detalles Bibliográficos
Autores principales: Shao, Ying, Zhang, Wenming, Du, Dongnian, Yu, Yi, Li, Qing, Peng, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550257/
https://www.ncbi.nlm.nih.gov/pubmed/36152057
http://dx.doi.org/10.18632/aging.204301