The Klotho protein supports redox balance and metabolic functions of cardiomyocytes during ischemia/reperfusion injury

BACKGROUND: Acute heart ischemia followed by reperfusion leads to overproduction of reactive oxygen/nitrogen species (ROS/RNS), disrupted expression of nitric oxide synthase (NOS) and unbalanced glucose metabolism. Klotho is a membrane-bound or soluble protein that exerts protective activity in many...

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Detalles Bibliográficos
Autores principales: Olejnik, Agnieszka, Banaszkiewicz, Marta, Krzywonos-Zawadzka, Anna, Bil-Lula, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Via Medica 2022
Materias:
Basic Science and Experimental Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550321/
https://www.ncbi.nlm.nih.gov/pubmed/34967938
http://dx.doi.org/10.5603/CJ.a2021.0174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550321/
https://www.ncbi.nlm.nih.gov/pubmed/34967938
http://dx.doi.org/10.5603/CJ.a2021.0174

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