Macrophage-Derived Exosomes in TLR9(−/−) Mice Ameliorate Sepsis-Induced Mitochondrial Oxidative Stress and Apoptosis in Cardiomyocytes

OBJECTIVE: To explore the mechanisms of TLR9 from macrophages on mitochondrial apoptosis in cardiomyocytes at early stage of sepsis. METHODS: The in vivo and in vitro sepsis mice were bone marrow transplantation (BMT) with wild type (WT) or (toll-like receptor 9) TLR9 knockout ((−/−) or KO) myeloid...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiang, Luo, Junyu, Li, Yanmei, Jia, Lu, Li, Yuejin, Ye, Shili, Liu, Lanlan, Yu, Yanxuan, Lu, Yonggang, Luan, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550441/
https://www.ncbi.nlm.nih.gov/pubmed/36225174
http://dx.doi.org/10.1155/2022/5719974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550441/
https://www.ncbi.nlm.nih.gov/pubmed/36225174
http://dx.doi.org/10.1155/2022/5719974

Ejemplares similares