HPLC Analytical Method Development and Validation of Gabapentin through Chemical Derivatization with Catechol as a Chromophore

BACKGROUND: Gabapentin is a drug with anticonvulsant activity and has been widely used in the treatment of epilepsy. Gabapentin chemical structure lacks a chromophore which makes its absorption very low and hence complicates its analysis and reduces the sensitivity of the method. Adding a chromophor...

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Detalles Bibliográficos
Autores principales: Abualhasan, Murad, Shraim, Fairouz, Alawni, Hiba, Hamdan, Saba, Khaseeb, Hadeel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550473/
https://www.ncbi.nlm.nih.gov/pubmed/36225344
http://dx.doi.org/10.1155/2022/3882682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550473/
https://www.ncbi.nlm.nih.gov/pubmed/36225344
http://dx.doi.org/10.1155/2022/3882682

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