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Overexpression of LncRNA MNX1-AS1/PPFIA4 Activates AKT/HIF-1α Signal Pathway to Promote Stemness of Colorectal Adenocarcinoma Cells

PURPOSE: The purpose of this study was to explore the role of the lncRNA MNX1-AS1 and its related downstream signaling pathways in colorectal adenocarcinoma (COAD). METHODS: COAD tissues and cells were prepared and treated with sh-MNX1-AS1, pcDNA-MNX1-AS1, sh-PPFIA4, LY29004, and their controls. CCK...

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Detalles Bibliográficos
Autores principales: Sun, Qi, Gui, Zhifu, Zhao, Zhenguo, Xu, Wenlong, Zhu, JunJia, Gao, Chundong, Zhao, Wei, Hu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550508/
https://www.ncbi.nlm.nih.gov/pubmed/36226248
http://dx.doi.org/10.1155/2022/8303409