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SEL1L-HRD1 ER-associated degradation suppresses hepatocyte hyperproliferation and liver cancer
Endoplasmic reticulum (ER) homeostasis has been implicated in the pathogenesis of various forms of cancer; however, our understanding of the role of ER quality control mechanisms in tumorigenesis remains incomplete. Here, we show that the SEL1L-HRD1 complex of ER-associated degradation (ERAD) suppre...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550610/ https://www.ncbi.nlm.nih.gov/pubmed/36238898 http://dx.doi.org/10.1016/j.isci.2022.105183 |