SEL1L-HRD1 ER-associated degradation suppresses hepatocyte hyperproliferation and liver cancer

Endoplasmic reticulum (ER) homeostasis has been implicated in the pathogenesis of various forms of cancer; however, our understanding of the role of ER quality control mechanisms in tumorigenesis remains incomplete. Here, we show that the SEL1L-HRD1 complex of ER-associated degradation (ERAD) suppre...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Asmita, Wei, Juncheng, Song, Wenxin, Gao, Beixue, Tian, Chunyan, Wu, Shuangcheng Alivia, Wang, Jian, Chen, Ligong, Fang, Deyu, Qi, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550610/
https://www.ncbi.nlm.nih.gov/pubmed/36238898
http://dx.doi.org/10.1016/j.isci.2022.105183

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