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Structural insights into PA3488-mediated inactivation of Pseudomonas aeruginosa PldA

PldA, a phospholipase D (PLD) effector, catalyzes hydrolysis of the phosphodiester bonds of glycerophospholipids—the main component of cell membranes—and assists the invasion of the opportunistic pathogen Pseudomonas aeruginosa. As a cognate immunity protein, PA3488 can inhibit the activity of PldA...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoyun, Li, Zongqiang, Zhao, Liang, She, Zhun, Gao, Zengqiang, Sui, Sen-Fang, Dong, Yuhui, Li, Yanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550806/
https://www.ncbi.nlm.nih.gov/pubmed/36216841
http://dx.doi.org/10.1038/s41467-022-33690-2