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Non-genetic stratification reveals epigenetic heterogeneity and identifies vulnerabilities of glycolysis addiction in lung adenocarcinoma subtype

Lung adenocarcinoma (LUAD) exhibits high heterogeneity and is well known for its high genetic variation. Recently, the understanding of non-genetic variation provides a new perspective to study the heterogeneity of LUAD. Little is known about whether super-enhancers (SEs) may be primarily responsibl...

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Detalles Bibliográficos
Autores principales: Song, Xuming, Zhang, Te, Ding, Hanlin, Feng, Yipeng, Yang, Wenmin, Yin, Xuewen, Chen, Bing, Liang, Yingkuan, Mao, Qixing, Xia, Wenjie, Yu, Guiping, Xu, Lin, Dong, Gaochao, Jiang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550819/
https://www.ncbi.nlm.nih.gov/pubmed/36216804
http://dx.doi.org/10.1038/s41389-022-00436-0