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One-pot H/D exchange and low-coordinated iron electrocatalyzed deuteration of nitriles in D(2)O to α,β-deuterio aryl ethylamines

Developing a step-economical approach for efficient synthesis of α,β-deuterio aryl ethylamines (α,β-DAEAs) with high deuterium ratios using an easy-to-handle deuterated source under ambient conditions is highly desirable. Here we report a room-temperature one-pot two-step transformation of aryl acet...

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Detalles Bibliográficos
Autores principales: Li, Rui, Wu, Yongmeng, Wang, Changhong, He, Meng, Liu, Cuibo, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550836/
https://www.ncbi.nlm.nih.gov/pubmed/36216818
http://dx.doi.org/10.1038/s41467-022-33779-8