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One-pot H/D exchange and low-coordinated iron electrocatalyzed deuteration of nitriles in D(2)O to α,β-deuterio aryl ethylamines
Developing a step-economical approach for efficient synthesis of α,β-deuterio aryl ethylamines (α,β-DAEAs) with high deuterium ratios using an easy-to-handle deuterated source under ambient conditions is highly desirable. Here we report a room-temperature one-pot two-step transformation of aryl acet...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550836/ https://www.ncbi.nlm.nih.gov/pubmed/36216818 http://dx.doi.org/10.1038/s41467-022-33779-8 |