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Exosomes secreted by hypoxia-stimulated bone-marrow mesenchymal stem cells promote grafted tendon-bone tunnel healing in rat anterior cruciate ligament reconstruction model

BACKGROUND: After anterior cruciate ligament (ACL) reconstruction in clinic, firm and rapid integration of the grafted tendon into the bone tunnel remains a challenge. Exosomes from hypoxia-treated stem cells are beneficial for promoting angiogenesis and then coupling with osteogenesis. Therefore, e...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Yan, Shaohang, Song, Ya, Chen, Can, Xu, Daqi, Lu, Bangbao, Xu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550857/
https://www.ncbi.nlm.nih.gov/pubmed/36263381
http://dx.doi.org/10.1016/j.jot.2022.08.001