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Dynamic SARS-CoV-2 emergence algorithm for rationally-designed logical next-generation vaccines

SARS-CoV-2 worldwide spread and evolution has resulted in variants containing mutations resulting in immune evasive epitopes that decrease vaccine efficacy. We acquired SARS-CoV-2 positive clinical samples and compared the worldwide emerged spike mutations from Variants of Concern/Interest, and deve...

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Detalles Bibliográficos
Autores principales: Maison, David P., Ching, Lauren L., Cleveland, Sean B., Tseng, Alanna C., Nakano, Eileen, Shikuma, Cecilia M., Nerurkar, Vivek R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550860/
https://www.ncbi.nlm.nih.gov/pubmed/36217024
http://dx.doi.org/10.1038/s42003-022-04030-3