Histone deacetylase 1 and 3 inhibitors alleviate colon inflammation by inhibiting Th17 cell differentiation

BACKGROUND: The etiology of inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is not completely clear, but its pathogenesis is closely related to T helper 17 (Th17) cells. Several histone deacetylase (HDAC) inhibitors have been shown to exert potent a...

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Detalles Bibliográficos
Autores principales: Gu, Zhengrong, Chen, Xiaotian, Zhu, Dandan, Wu, Songting, Yu, Chenggong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550981/
https://www.ncbi.nlm.nih.gov/pubmed/36106389
http://dx.doi.org/10.1002/jcla.24699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550981/
https://www.ncbi.nlm.nih.gov/pubmed/36106389
http://dx.doi.org/10.1002/jcla.24699

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