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Activation of cGAS‐STING pathway – A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune‐mediated necrotizing myopathy

OBJECTIVE: The objective was to investigate the expression of the cGAS‐STING pathway‐associated protein in idiopathic inflammatory myopathy (IIM) and to investigate whether it is related to myofiber atrophy/necrosis in patients with dermatomyositis and immune‐mediated necrotizing myopathy. MATERIAL...

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Detalles Bibliográficos
Autores principales: Zhou, Meichen, Cheng, Xiaoxiao, Zhu, Wenhua, Jiang, Jianhua, Zhu, Sijia, Wu, Xuan, Liu, Meirong, Fang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550984/
https://www.ncbi.nlm.nih.gov/pubmed/36030554
http://dx.doi.org/10.1002/jcla.24631