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Age-linked suppression of lipoxin A4 associates with cognitive deficits in mice and humans

Age increases the risk for cognitive impairment and is the single major risk factor for Alzheimer’s disease (AD), the most prevalent form of dementia in the elderly. The pathophysiological processes triggered by aging that render the brain vulnerable to dementia involve, at least in part, changes in...

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Detalles Bibliográficos
Autores principales: Pamplona, Fabricio A., Vitória, Gabriela, Sudo, Felipe K., Ribeiro, Felipe C., Isaac, Alinny R., Moraes, Carolina A., Chauvet, Mariana G., Ledur, Pitia Flores, Karmirian, Karina, Ornelas, Isis M., Leo, Luciana M., Paulsen, Bruna, Coutinho, Gabriel, Drummond, Claudia, Assunção, Naima, Vanderborght, Bart, Canetti, Claudio A., Castro-Faria-Neto, Hugo C., Mattos, Paulo, Ferreira, Sergio T., Rehen, Stevens K., Bozza, Fernando A., Lourenco, Mychael V., Tovar-Moll, Fernanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551034/
https://www.ncbi.nlm.nih.gov/pubmed/36216800
http://dx.doi.org/10.1038/s41398-022-02208-1