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Age-linked suppression of lipoxin A4 associates with cognitive deficits in mice and humans
Age increases the risk for cognitive impairment and is the single major risk factor for Alzheimer’s disease (AD), the most prevalent form of dementia in the elderly. The pathophysiological processes triggered by aging that render the brain vulnerable to dementia involve, at least in part, changes in...
Autores principales: | Pamplona, Fabricio A., Vitória, Gabriela, Sudo, Felipe K., Ribeiro, Felipe C., Isaac, Alinny R., Moraes, Carolina A., Chauvet, Mariana G., Ledur, Pitia Flores, Karmirian, Karina, Ornelas, Isis M., Leo, Luciana M., Paulsen, Bruna, Coutinho, Gabriel, Drummond, Claudia, Assunção, Naima, Vanderborght, Bart, Canetti, Claudio A., Castro-Faria-Neto, Hugo C., Mattos, Paulo, Ferreira, Sergio T., Rehen, Stevens K., Bozza, Fernando A., Lourenco, Mychael V., Tovar-Moll, Fernanda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551034/ https://www.ncbi.nlm.nih.gov/pubmed/36216800 http://dx.doi.org/10.1038/s41398-022-02208-1 |
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