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Ni-catalyzed carbamoylation of unactivated alkenes for stereoselective construction of six-membered lactams

Nitrogen-based heterocycles have aroused widespread interest due to their reoccurrence in many pharmaceuticals. Amongst these motifs, the enantioenriched lactams are the ubiquitous scaffolds found in myriad biologically active natural products and drugs. Recently, the transition metal-catalyzed asym...

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Detalles Bibliográficos
Autores principales: Zhang, Chenhuan, Wu, Xianqing, Xia, Tingting, Qu, Jingping, Chen, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551058/
https://www.ncbi.nlm.nih.gov/pubmed/36216794
http://dx.doi.org/10.1038/s41467-022-33425-3