Quinoline–imidazole/benzimidazole derivatives as dual-/multi-targeting hybrids inhibitors with anticancer and antimicrobial activity

Two new classes of hybrid quinoline–imidazole/benzimidazole derivatives (the hybrid QIBS salts and QIBC cycloadducts) were designed and synthesized to evaluate their anticancer and antimicrobial activity. The strategy adopted for synthesis is straight and efficient, in four steps: N-acylation, N-alk...

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Detalles Bibliográficos
Autores principales: Diaconu, Dumitrela, Antoci, Vasilichia, Mangalagiu, Violeta, Amariucai-Mantu, Dorina, Mangalagiu, Ionel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551061/
https://www.ncbi.nlm.nih.gov/pubmed/36216981
http://dx.doi.org/10.1038/s41598-022-21435-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551061/
https://www.ncbi.nlm.nih.gov/pubmed/36216981
http://dx.doi.org/10.1038/s41598-022-21435-6

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