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The iron–sulfur cluster assembly (ISC) protein Iba57 executes a tetrahydrofolate-independent function in mitochondrial [4Fe–4S] protein maturation

Mitochondria harbor the bacteria-inherited iron–sulfur cluster assembly (ISC) machinery to generate [2Fe–2S; iron–sulfur (Fe–S)] and [4Fe–4S] proteins. In yeast, assembly of [4Fe–4S] proteins specifically involves the ISC proteins Isa1, Isa2, Iba57, Bol3, and Nfu1. Functional defects in their human...

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Detalles Bibliográficos
Autores principales: Mühlenhoff, Ulrich, Weiler, Benjamin Dennis, Nadler, Franziska, Millar, Robert, Kothe, Isabell, Freibert, Sven-Andreas, Altegoer, Florian, Bange, Gert, Lill, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551070/
https://www.ncbi.nlm.nih.gov/pubmed/36075292
http://dx.doi.org/10.1016/j.jbc.2022.102465