NRSF/REST lies at the intersection between epigenetic regulation, miRNA-mediated gene control and neurodevelopmental pathways associated with Intellectual disability (ID) and Schizophrenia

Genetic evidence indicates disrupted epigenetic regulation as a major risk factor for psychiatric disorders, but the molecular mechanisms that drive this association remain to be determined. EHMT1 is an epigenetic repressor that is causal for Kleefstra Syndrome (KS), a genetic disorder linked with n...

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Detalles Bibliográficos
Autores principales: Alsaqati, Mouhamed, Davis, Brittany A., Wood, Jamie, Jones, Megan M., Jones, Lora, Westwood, Aishah, Petter, Olena, Isles, Anthony R., Linden, David, Van den Bree, Marianne, Owen, Michael, Hall, Jeremy, Harwood, Adrian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551101/
https://www.ncbi.nlm.nih.gov/pubmed/36216811
http://dx.doi.org/10.1038/s41398-022-02199-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551101/
https://www.ncbi.nlm.nih.gov/pubmed/36216811
http://dx.doi.org/10.1038/s41398-022-02199-z

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