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ICAT promotes colorectal cancer metastasis via binding to JUP and activating the NF‐κB signaling pathway

BACKGROUND: The inhibitor of β‐catenin and T‐cell factor (ICAT) is a direct negative regulator of the canonical Wnt signaling pathway, which is an attractive therapeutic target for colorectal cancer (CRC). Accumulating evidence suggests that ICAT interacts with other proteins to exert additional fun...

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Detalles Bibliográficos
Autores principales: Wang, Zihan, Hu, Jiancong, Chen, Junxiong, Zhang, Jingdan, Li, Weiqian, Tian, Yu, Liu, Huanliang, Yang, Xiangling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551128/
https://www.ncbi.nlm.nih.gov/pubmed/36036768
http://dx.doi.org/10.1002/jcla.24678