Cargando…

Disruption of adipocyte YAP improves glucose homeostasis in mice and decreases adipose tissue fibrosis

OBJECTIVE: Adipose tissue is a very dynamic metabolic organ that plays an essential role in regulating whole-body glucose homeostasis. Dysfunctional adipose tissue hypertrophy with obesity is associated with fibrosis and type 2 diabetes. Yes-associated protein 1 (YAP) is a transcription cofactor imp...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Daniel J., Aslam, Rukhsana, Misra, Paraish S., Chiu, Felix, Ojha, Tanvi, Chowdhury, Apu, Chan, Carmen K., Sung, Hoon-Ki, Yuen, Darren A., Luk, Cynthia T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551211/
https://www.ncbi.nlm.nih.gov/pubmed/36165813
http://dx.doi.org/10.1016/j.molmet.2022.101594