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Disruption of adipocyte YAP improves glucose homeostasis in mice and decreases adipose tissue fibrosis
OBJECTIVE: Adipose tissue is a very dynamic metabolic organ that plays an essential role in regulating whole-body glucose homeostasis. Dysfunctional adipose tissue hypertrophy with obesity is associated with fibrosis and type 2 diabetes. Yes-associated protein 1 (YAP) is a transcription cofactor imp...
Autores principales: | Han, Daniel J., Aslam, Rukhsana, Misra, Paraish S., Chiu, Felix, Ojha, Tanvi, Chowdhury, Apu, Chan, Carmen K., Sung, Hoon-Ki, Yuen, Darren A., Luk, Cynthia T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551211/ https://www.ncbi.nlm.nih.gov/pubmed/36165813 http://dx.doi.org/10.1016/j.molmet.2022.101594 |
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