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Breviscapine remodels myocardial glucose and lipid metabolism by regulating serotonin to alleviate doxorubicin-induced cardiotoxicity

Aims: The broad-spectrum anticancer drug doxorubicin (Dox) is associated with a high incidence of cardiotoxicity, which severely affects the clinical application of the drug and patients’ quality of life. Here, we assess how Dox modulates myocardial energy and contractile function and this could aid...

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Detalles Bibliográficos
Autores principales: Li, Meng-Jiao, Sun, Wen-She, Yuan, Yang, Zhang, Yu-Kun, Lu, Qi, Gao, Yuan-Zhen, Ye, Ting, Xing, Dong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551275/
https://www.ncbi.nlm.nih.gov/pubmed/36238546
http://dx.doi.org/10.3389/fphar.2022.930835