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Acute Manganese Exposure Modifies the Translation Machinery via PI3K/Akt Signaling in Glial Cells

Manganese (Mn) exerts serious neurotoxic effects, among which, the disruption of the glutamate/glutamine (Glu/Gln) cycle, leads to an excitotoxic insult. The molecular mechanisms mediating Mn-induced neurotoxicity, have not yet been fully understood. Glu, the major excitatory neurotransmitter in the...

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Detalles Bibliográficos
Autores principales: Soto-Verdugo, Jzmín, Siva-Parra, Janisse, Hernández-Kelly, Luisa C, Ortega, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551334/
https://www.ncbi.nlm.nih.gov/pubmed/36203371
http://dx.doi.org/10.1177/17590914221131452