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Acute Manganese Exposure Modifies the Translation Machinery via PI3K/Akt Signaling in Glial Cells
Manganese (Mn) exerts serious neurotoxic effects, among which, the disruption of the glutamate/glutamine (Glu/Gln) cycle, leads to an excitotoxic insult. The molecular mechanisms mediating Mn-induced neurotoxicity, have not yet been fully understood. Glu, the major excitatory neurotransmitter in the...
Autores principales: | Soto-Verdugo, Jzmín, Siva-Parra, Janisse, Hernández-Kelly, Luisa C, Ortega, Arturo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551334/ https://www.ncbi.nlm.nih.gov/pubmed/36203371 http://dx.doi.org/10.1177/17590914221131452 |
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