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Identification of four immune subtypes in locally advanced rectal cancer treated with neoadjuvant chemotherapy for predicting the efficacy of subsequent immune checkpoint blockade

INTRODUCTION: Neoadjuvant chemoradiotherapy (nCRT) is the foundation treatment for locally advanced rectal cancer (LARC). The nCRT can improve the efficacy of immunotherapy because of its in situ vaccine effect. OBJECTIVE: The aim is to identify stable and reliable transcriptome signatures to predic...

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Detalles Bibliográficos
Autores principales: He, Le, Jin, Min, Jian, Dan, Yang, Bo, Dai, Nan, Feng, Yan, Xiao, He, Wang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551659/
https://www.ncbi.nlm.nih.gov/pubmed/36238279
http://dx.doi.org/10.3389/fimmu.2022.955187