Selumetinib - a potential small molecule inhibitor for osteoarthritis treatment

Objectives: Osteoarthritis (OA) is a common disease that mainly manifests as inflammation and destruction of cartilage and subchondral bone. Recently, necroptosis has been reported to play an important role in the development of OA. Selumetinib displays a contrasting expression pattern to necroptosi...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaohang, Qiu, Jianxin, Pan, Wenjun, Gong, Yuhang, Zhang, Weikang, Jiang, Ting, Chen, Lihua, Chen, Weifu, Hong, Zhenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552066/
https://www.ncbi.nlm.nih.gov/pubmed/36238555
http://dx.doi.org/10.3389/fphar.2022.938133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552066/
https://www.ncbi.nlm.nih.gov/pubmed/36238555
http://dx.doi.org/10.3389/fphar.2022.938133

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