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An interpretable stacking ensemble learning framework based on multi-dimensional data for real-time prediction of drug concentration: The example of olanzapine

Background and Aim: Therapeutic drug monitoring (TDM) has evolved over the years as an important tool for personalized medicine. Nevertheless, some limitations are associated with traditional TDM. Emerging data-driven model forecasting [e.g., through machine learning (ML)-based approaches] has been...

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Detalles Bibliográficos
Autores principales: Zhu, Xiuqing, Hu, Jinqing, Xiao, Tao, Huang, Shanqing, Wen, Yuguan, Shang, Dewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552071/
https://www.ncbi.nlm.nih.gov/pubmed/36238557
http://dx.doi.org/10.3389/fphar.2022.975855