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The evolutionary conservation of eukaryotic membrane-bound adenylyl cyclase isoforms
The nine membrane-delimited eukaryotic adenylyl cyclases are pseudoheterodimers with an identical domain order of seven (nine) distinct subdomains. Bioinformatics show that the protein evolved from a monomeric bacterial progenitor by gene duplication and fusion probably in a primordial eukaryotic ce...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552081/ https://www.ncbi.nlm.nih.gov/pubmed/36238545 http://dx.doi.org/10.3389/fphar.2022.1009797 |