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Generation of murine tumour-reactive T cells by co-culturing murine pancreatic cancer organoids and peripheral blood lymphocytes

Pancreatic ductal adenocarcinoma (PDAC) is commonly diagnosed at a late stage and becomes resistant to several treatments. Significant clinical effects have been reported for cancer immunotherapies on a subset of patients diagnosed with epithelial cancers. Cancer organoid co-culture with autologous...

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Detalles Bibliográficos
Autores principales: D'Angelo, Alberto, Shibata, Kensuke, Tokunaga, Masayuki, Furutani-Seiki, Makoto, Bagby, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552097/
https://www.ncbi.nlm.nih.gov/pubmed/36237445
http://dx.doi.org/10.1016/j.bbrep.2022.101365