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A Bifurcated Multicomponent Synthesis Approach to Polycyclic Quinazolinones

[Image: see text] The rapid synthesis of diverse substituted polycyclic quinazolinones was achieved by two orthogonal Ugi four-component reaction (Ugi-4CR)-based protocols: the first two-step approach via an ammonia-Ugi-4CR followed by palladium-catalyzed annulation; in the second approach, cyanamid...

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Detalles Bibliográficos
Autores principales: Xu, Ruixue, Wang, Zefeng, Zheng, Qiang, Patil, Pravin, Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552225/
https://www.ncbi.nlm.nih.gov/pubmed/36095044
http://dx.doi.org/10.1021/acs.joc.2c01561