Synthesis of Optically Active syn- and anti-Chlorohydrins through a Bienzymatic Reductive Cascade

[Image: see text] A bienzymatic cascade has been designed and optimized to obtain enantiopure chlorohydrins starting from the corresponding 1-aryl-2-chlorobut-2-en-1-ones. For the synthesis of these α-chloroenones, a two-step sequence was developed consisting of the allylation of the corresponding a...

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Detalles Bibliográficos
Autores principales: González-Rodríguez, Jorge, Albarrán-Velo, Jesús, Soengas, Raquel G., Lavandera, Iván, Gotor-Fernández, Vicente, Rodríguez-Solla, Humberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552227/
https://www.ncbi.nlm.nih.gov/pubmed/36154101
http://dx.doi.org/10.1021/acs.orglett.2c02592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552227/
https://www.ncbi.nlm.nih.gov/pubmed/36154101
http://dx.doi.org/10.1021/acs.orglett.2c02592

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