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Synthesis of Optically Active syn- and anti-Chlorohydrins through a Bienzymatic Reductive Cascade
[Image: see text] A bienzymatic cascade has been designed and optimized to obtain enantiopure chlorohydrins starting from the corresponding 1-aryl-2-chlorobut-2-en-1-ones. For the synthesis of these α-chloroenones, a two-step sequence was developed consisting of the allylation of the corresponding a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552227/ https://www.ncbi.nlm.nih.gov/pubmed/36154101 http://dx.doi.org/10.1021/acs.orglett.2c02592 |