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Addressing the Protease Bias in Quantitative Proteomics

[Image: see text] Protein quantification strategies using multiple proteases have been shown to deliver poor interprotease accuracy in label-free mass spectrometry experiments. By utilizing six different proteases with different cleavage sites, this study explores the protease bias and its effect on...

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Detalles Bibliográficos
Autores principales: Woessmann, Jakob, Kotol, David, Hober, Andreas, Uhlén, Mathias, Edfors, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552229/
https://www.ncbi.nlm.nih.gov/pubmed/36044728
http://dx.doi.org/10.1021/acs.jproteome.2c00491