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Addressing the Protease Bias in Quantitative Proteomics
[Image: see text] Protein quantification strategies using multiple proteases have been shown to deliver poor interprotease accuracy in label-free mass spectrometry experiments. By utilizing six different proteases with different cleavage sites, this study explores the protease bias and its effect on...
Autores principales: | Woessmann, Jakob, Kotol, David, Hober, Andreas, Uhlén, Mathias, Edfors, Fredrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552229/ https://www.ncbi.nlm.nih.gov/pubmed/36044728 http://dx.doi.org/10.1021/acs.jproteome.2c00491 |
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