Targeted therapy in NPM1-mutated AML: Knowns and unknowns

Acute myeloid leukemia (AML) is a heterogeneous disease characterized by malignant proliferation of myeloid hematopoietic stem/progenitor cells. NPM1 represents the most frequently mutated gene in AML and approximately 30% of AML cases carry NPM1 mutations. Mutated NPM1 result in the cytoplasmic loc...

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Detalles Bibliográficos
Autores principales: Wang, Rong, Xu, Pan, Chang, Lin-Lin, Zhang, Shi-Zhong, Zhu, Hong-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552319/
https://www.ncbi.nlm.nih.gov/pubmed/36237321
http://dx.doi.org/10.3389/fonc.2022.972606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552319/
https://www.ncbi.nlm.nih.gov/pubmed/36237321
http://dx.doi.org/10.3389/fonc.2022.972606

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