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Managing clustering effects and learning effects in the design and analysis of randomised surgical trials: a review of existing guidance
BACKGROUND: The complexities associated with delivering randomised surgical trials, such as clustering effects, by centre or surgeon, and surgical learning, are well known. Despite this, approaches used to manage these complexities, and opinions on these, vary. Guidance documents have been developed...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552436/ https://www.ncbi.nlm.nih.gov/pubmed/36221107 http://dx.doi.org/10.1186/s13063-022-06743-6 |