Serum total TDP-43 levels are decreased in frontotemporal dementia patients with C9orf72 repeat expansion or concomitant motoneuron disease phenotype

BACKGROUND: Frontotemporal dementia (FTD) covers a spectrum of neurodegenerative disorders with various clinical and neuropathological subtypes. The two major pathological proteins accumulating in the brains of FTD patients, depending on their genetic background, are TDP-43 and tau. We aimed to eval...

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Detalles Bibliográficos
Autores principales: Katisko, Kasper, Huber, Nadine, Kokkola, Tarja, Hartikainen, Päivi, Krüger, Johanna, Heikkinen, Anna-Leena, Paananen, Veera, Leinonen, Ville, Korhonen, Ville E., Helisalmi, Seppo, Herukka, Sanna-Kaisa, Cantoni, Valentina, Gadola, Yasmine, Archetti, Silvana, Remes, Anne M., Haapasalo, Annakaisa, Borroni, Barbara, Solje, Eino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552448/
https://www.ncbi.nlm.nih.gov/pubmed/36217158
http://dx.doi.org/10.1186/s13195-022-01091-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552448/
https://www.ncbi.nlm.nih.gov/pubmed/36217158
http://dx.doi.org/10.1186/s13195-022-01091-8

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