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Comparative transcriptomics in human COPD reveals dysregulated genes uniquely expressed in ferrets

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a progressive lung disease with poor treatment options. However, most mouse models of COPD produce a primarily emphysematous disease not recapitulating clinically meaningful COPD features like chronic bronchitis. METHODS: Wild-type ferrets...

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Detalles Bibliográficos
Autores principales: Hussain, Shah S., Edwards, Yvonne J. K., Libby, Emily Falk, Stanford, Denise, Byzek, Stephen A., Sin, Don D., McDonald, Merry-Lynn, Raju, S. Vamsee, Rowe, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552453/
https://www.ncbi.nlm.nih.gov/pubmed/36217144
http://dx.doi.org/10.1186/s12931-022-02198-0