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STAT3/miR-130b-3p/MBNL1 feedback loop regulated by mTORC1 signaling promotes angiogenesis and tumor growth

BACKGROUND: Aberrantly activated mammalian target of rapamycin complex 1 (mTORC1) plays a vital role in tumor angiogenesis, but its precise mechanisms are still unclear. METHODS: Micro-RNA-130b-3p (miR-130b-3p) expression in mTORC1-activated and control cells was examined by quantitative real-time P...

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Detalles Bibliográficos
Autores principales: Li, Hongwu, Liu, Ping, Li, Dapeng, Wang, Zixi, Ding, Zhao, Zhou, Meng, Chen, Xu, Miao, Manli, Ding, Junli, Lin, Wei, Liu, Yehai, Zha, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552455/
https://www.ncbi.nlm.nih.gov/pubmed/36217202
http://dx.doi.org/10.1186/s13046-022-02513-z