Post-transcriptional regulatory feedback encodes JAK-STAT signal memory of interferon stimulation

Immune cells fine tune their responses to infection and inflammatory cues. Here, using live-cell confocal microscopy and mathematical modelling, we investigate interferon-induced JAK-STAT signalling in innate immune macrophages. We demonstrate that transient exposure to IFN-γ stimulation induces a l...

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Detalles Bibliográficos
Autores principales: Kalliara, Eirini, Kardynska, Malgorzata, Bagnall, James, Spiller, David G., Müller, Werner, Ruckerl, Dominik, Śmieja, Jarosław, Biswas, Subhra K., Paszek, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552616/
https://www.ncbi.nlm.nih.gov/pubmed/36238296
http://dx.doi.org/10.3389/fimmu.2022.947213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552616/
https://www.ncbi.nlm.nih.gov/pubmed/36238296
http://dx.doi.org/10.3389/fimmu.2022.947213

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