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Development of immunohistochemistry for detecting fluvoxamine in rat tissues using newly prepared monoclonal antibody: its precise localization in small intestine, kidney, and liver of rats

A monoclonal antibody (mAb) was produced against a fluvoxamine (FLV)-bovine serum albumin conjugate that was specific to both the conjugate and free form of FLV. The mAb enabled us to develop an immunohistochemistry (IHC) method for pharmacokinetic analysis of FLV at the cell and tissue levels. We d...

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Detalles Bibliográficos
Autores principales: Shin, Masashi, Yamamoto, Yutaro, Kataoka, Hiroto, Saita, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552737/
https://www.ncbi.nlm.nih.gov/pubmed/36219258
http://dx.doi.org/10.1007/s00795-022-00337-6