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Tbx18 Orchestrates Cytostructural Transdifferentiation of Cardiomyocytes to Pacemaker Cells by Recruiting the Epithelial–Mesenchymal Transition Program

[Image: see text] Previously, we reported that heterologous expression of an embryonic transcription factor, Tbx18, reprograms ventricular cardiomyocytes into induced pacemaker cells (Tbx18-iPMs), though the key pathways are unknown. Here, we have used a tandem mass tag proteomic approach to charact...

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Detalles Bibliográficos
Autores principales: Foster, D. Brian, Gu, Jin-mo, Kim, Elizabeth H., Wolfson, David W., O’Meally, Robert, Cole, Robert N., Cho, Hee Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552783/
https://www.ncbi.nlm.nih.gov/pubmed/36006872
http://dx.doi.org/10.1021/acs.jproteome.2c00133