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PTEN loss promotes Warburg effect and prostate cancer cell growth by inducing FBP1 degradation
RATIONALE: Fructose-1,6-bisphosphatase (FBP1) is a tumor suppressor and a key enzyme negatively regulating Warburg effect in cancer. However, regulation of FBP1 protein expression and its exact role in prostate cancer (PCa) is largely unclear. Phosphatase and tensin homolog (PTEN) is one of the most...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552847/ https://www.ncbi.nlm.nih.gov/pubmed/36237339 http://dx.doi.org/10.3389/fonc.2022.911466 |