Cargando…

PTEN loss promotes Warburg effect and prostate cancer cell growth by inducing FBP1 degradation

RATIONALE: Fructose-1,6-bisphosphatase (FBP1) is a tumor suppressor and a key enzyme negatively regulating Warburg effect in cancer. However, regulation of FBP1 protein expression and its exact role in prostate cancer (PCa) is largely unclear. Phosphatase and tensin homolog (PTEN) is one of the most...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Changze, Zhang, Jianong, Liu, Xiao, Li, Meilu, Wang, Dejie, Kang, Zhijian, Yu, Jiaao, Chen, Jiuwei, Pan, Hongxin, Wang, Honglei, Li, Guangbin, Huang, Haojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552847/
https://www.ncbi.nlm.nih.gov/pubmed/36237339
http://dx.doi.org/10.3389/fonc.2022.911466