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Unraveling tumor microenvironment heterogeneity in malignant pleural mesothelioma identifies biologically distinct immune subtypes enabling prognosis determination

BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare and intractable disease exhibiting a remarkable intratumoral heterogeneity and dismal prognosis. Although immunotherapy has reshaped the therapeutic strategies for MPM, patients react with discrepant responsiveness. METHODS: Herein, we recru...

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Detalles Bibliográficos
Autores principales: Yang, Kaidi, Yang, Tongxin, Yang, Tao, Yuan, Ye, Li, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552848/
https://www.ncbi.nlm.nih.gov/pubmed/36237331
http://dx.doi.org/10.3389/fonc.2022.995651