Cargando…

Unraveling tumor microenvironment heterogeneity in malignant pleural mesothelioma identifies biologically distinct immune subtypes enabling prognosis determination

BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare and intractable disease exhibiting a remarkable intratumoral heterogeneity and dismal prognosis. Although immunotherapy has reshaped the therapeutic strategies for MPM, patients react with discrepant responsiveness. METHODS: Herein, we recru...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Kaidi, Yang, Tongxin, Yang, Tao, Yuan, Ye, Li, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552848/ https://www.ncbi.nlm.nih.gov/pubmed/36237331 http://dx.doi.org/10.3389/fonc.2022.995651

Ejemplares similares

Immune Microenvironment and Genetics in Malignant Pleural Mesothelioma
por: Wadowski, Benjamin, et al.
Publicado: (2021)

Tumor Microenvironment-Associated Immune-Related Genes for the Prognosis of Malignant Pleural Mesothelioma
por: Xu, Xiaoling, et al.
Publicado: (2020)

P14/ARF-Positive Malignant Pleural Mesothelioma: A Phenotype With Distinct Immune Microenvironment
por: Pezzuto, Federica, et al.
Publicado: (2021)

Immunotherapy in Malignant Pleural Mesothelioma
por: de Gooijer, Cornedine J., et al.
Publicado: (2020)

Reveal the Heterogeneity in the Tumor Microenvironment of Pancreatic Cancer and Analyze the Differences in Prognosis and Immunotherapy Responses of Distinct Immune Subtypes
por: Wang, Xiaoqin, et al.
Publicado: (2022)

Heterogeneity in Malignant Pleural Mesothelioma
por: Oehl, Kathrin, et al.
Publicado: (2018)

Current State of Pleural-Directed Adjuncts Against Malignant Pleural Mesothelioma
por: Choi, Agnes Y., et al.
Publicado: (2022)

Prognostic Role of Tumor Immune Microenvironment in Pleural Epithelioid Mesothelioma
por: Ollila, Hely, et al.
Publicado: (2022)

Unraveling tumour microenvironment heterogeneity in nasopharyngeal carcinoma identifies biologically distinct immune subtypes predicting prognosis and immunotherapy responses
por: Chen, Yu-Pei, et al.
Publicado: (2021)

New Perspectives on Diagnosis and Therapy of Malignant Pleural Mesothelioma
por: Rossini, Marika, et al.
Publicado: (2018)

Therapeutic Landscape of Malignant Pleural Mesothelioma: Collateral Vulnerabilities and Evolutionary Dependencies in the Spotlight
por: Xu, Duo, et al.
Publicado: (2020)

Development and Validation of a Prognostic Signature for Malignant Pleural Mesothelioma
por: Zhou, Jian-Guo, et al.
Publicado: (2019)

Emerging Treatments for Malignant Pleural Mesothelioma: Where Are We Heading?
por: Cantini, Luca, et al.
Publicado: (2020)

Clinical significance of histologic subtyping of malignant pleural mesothelioma
por: Brcic, Luka, et al.
Publicado: (2020)

Interobserver Agreement in Histopathological Subtyping of Malignant Pleural Mesotheliomas
por: Mlika, Mona, et al.
Publicado: (2021)

Liquid Biopsy in Malignant Pleural Mesothelioma: State of the Art, Pitfalls, and Perspectives
por: Cavallari, Ilaria, et al.
Publicado: (2019)

Cellular Immunotherapy and Locoregional Administration of CAR T-Cells in Malignant Pleural Mesothelioma
por: Belderbos, Robert A., et al.
Publicado: (2020)

Malignant Pleural Mesothelioma: State-of-the-Art on Current Therapies and Promises for the Future
por: Nicolini, Fabio, et al.
Publicado: (2020)

Malignant Pleural Mesothelioma Epidemiology in the United States From 2000 to 2016
por: Thomas, Akesh, et al.
Publicado: (2021)

Editorial: Advances in malignant pleural mesothelioma: Diagnosis, treatment, and molecular mechanisms
por: Mastromarino, Maria Giovanna, et al.
Publicado: (2023)

Heterogeneity in Immune Cell Content in Malignant Pleural Mesothelioma
por: Minnema-Luiting, Jorien, et al.
Publicado: (2018)

Define the Two Molecular Subtypes of Epithelioid Malignant Pleural Mesothelioma
por: Saddozai, Umair Ali Khan, et al.
Publicado: (2022)

MicroRNAs for the Diagnosis and Management of Malignant Pleural Mesothelioma: A Literature Review
por: Lo Russo, Giuseppe, et al.
Publicado: (2018)

Manipulating microRNAs for the Treatment of Malignant Pleural Mesothelioma: Past, Present and Future
por: Reid, Glen, et al.
Publicado: (2020)

Circulating Epigenetic Biomarkers in Malignant Pleural Mesothelioma: State of the Art and critical Evaluation
por: Ferrari, Luca, et al.
Publicado: (2020)

Complete Pathological Response After Neoadjuvant Chemo-Immunotherapy in Malignant Pleural Mesothelioma
por: Tostes, Francinne T., et al.
Publicado: (2022)

The Immune Microenvironment of Malignant Pleural Mesothelioma: A Literature Review
por: Désage, Anne-Laure, et al.
Publicado: (2021)

Malignant pleural mesothelioma
por: Rao, Sukhesh
Publicado: (2009)

Cerebral Metastasis of a Malignant Pleural Mesothelioma: A Case Report and Review of the Literature
por: Chari, Aswin, et al.
Publicado: (2015)

Unexplained Pleural Effusion Leads to the Revelation of a Malignant Mesothelioma: A Case Report
por: Rhazari, Meriem, et al.
Publicado: (2022)

Genomics of Tumor Origin and Characteristics for Adenocarcinoma and Malignant Pleural Mesothelioma: A Case Report
por: Usuda, Katsuo, et al.
Publicado: (2022)

SEOM clinical guidelines for the treatment of malignant pleural mesothelioma (2020)
por: Nadal, E., et al.
Publicado: (2021)

Comparative proteomic analysis of malignant pleural mesothelioma: Focusing on the biphasic subtype
por: Giusti, Laura, et al.
Publicado: (2016)

Pathological Characterization of Tumor Immune Microenvironment (TIME) in Malignant Pleural Mesothelioma
por: Napoli, Francesca, et al.
Publicado: (2021)

Clinical experience of volumetric modulated arc therapy for malignant pleural mesothelioma after extrapleural pneumonectomy
por: Kimura, Tomoki, et al.
Publicado: (2015)

A Community-Driven, Openly Accessible Molecular Pathway Integrating Knowledge on Malignant Pleural Mesothelioma
por: Martens, Marvin, et al.
Publicado: (2022)

Diagnostic value of combination of biomarkers for malignant pleural mesothelioma: a systematic review and meta-analysis
por: Zhu, Mucheng, et al.
Publicado: (2023)

SMO mutations confer poor prognosis in malignant pleural mesothelioma
por: Signorelli, Diego, et al.
Publicado: (2020)

Radiation Induced Abscopal Effect in a Patient With Malignant Pleural Mesothelioma on Pembrolizumab
por: Rittberg, Rebekah, et al.
Publicado: (2022)

Microenvironment-Dependent Phenotypic Changes in a SCID Mouse Model for Malignant Mesothelioma
por: Darai-Ramqvist, Eva, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_furrqdqasmqqf0b5tnohquhrap