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The two facets of receptor tyrosine kinase in cardiovascular calcification—can tyrosine kinase inhibitors benefit cardiovascular system?

Tyrosine kinase inhibitors (TKIs) are widely used in cancer treatment due to their effectiveness in cancer cell killing. However, an off-target of this agent limits its success. Cardiotoxicity-associated TKIs have been widely reported. Tyrosine kinase is involved in many regulatory processes in a ce...

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Detalles Bibliográficos
Autores principales: Masbuchin, Ainun Nizar, Widodo, Rohman, Mohammad Saifur, Liu, Ping-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552878/
https://www.ncbi.nlm.nih.gov/pubmed/36237897
http://dx.doi.org/10.3389/fcvm.2022.986570