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An Adjuvant-Free Mouse Model Using Skin Sensitization Without Tape-Stripping Followed by Oral Elicitation of Anaphylaxis: A Novel Pre-Clinical Tool for Testing Intrinsic Wheat Allergenicity

Wheat is a major food allergen per the regulatory bodies of various nations. Hypersensitivity reactions to wheat have been steadily increasing for reasons that are not completely understood. Wheat-allergy models typically use adjuvants to induce sensitization to wheat proteins followed by an intrape...

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Detalles Bibliográficos
Autores principales: Gao, Haoran, Jorgensen, Rick, Raghunath, Rajsri, Ng, Perry K. W., Gangur, Venu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552944/
https://www.ncbi.nlm.nih.gov/pubmed/36238931
http://dx.doi.org/10.3389/falgy.2022.926576